Muscle Histology Changes

Acta Myol, 2016; 34(2-3): 133-8, PMID: 27199541 external link

Muscle histology changes after short term vibration training in healthy controls

Schoser B
Friedrich-Baur-Institute, Department of Neurology, Klinikum der Universitat Munchen, Germany.


Purpose: In search for additional counter measures of muscle atrophy vibration exercise training may have substantial effort for patients with neuromuscular disorders. To cover safety aspects and obtain muscle morphology data, a pilot study was performed in eleven healthy men.

Method: Countermovement jump, squat jump, drop jump and one repetition maximum test (1RM) were performed on a force platform before and after a 6 week training period. No severe side effects were found.

Results: Repeated needle muscle biopsies of the vastus lateralis muscle revealed a selective pre- to post-training type-2 myofiber hypertrophy of up to 50 %. The hypertrophy factors were 160 and 310, for type-2 myofibers. The mechanography system showed a significant increase in the 1RM maximum weight lifted (pre: 111,8 kg +/- 11,5; post: 140,9 kg +/- 13,00; p < 0,001).

Conclusion: Vibration exercise is a safe and effective technique which desires further approval as counter measure in different types of neuromuscular atrophy.